Gastric neuroendocrine hyperplasia and dysplasia in a patient with Lynch syndrome

Lynch syndrome (LS) is a common hereditary caused by mutations in deoxyribonucleic acid mismatch repair genes, with high probability of gastrointestinal, gynaecological and other cancers. The most LS-associated gastric cancer adenocarcinoma the intestinal type. Neuroendocrine neoplasia has not been well understood cancer. Herein, we report case 68-year-old female, history ascending colon seven years ago, now presenting as synchronous mixed type mucinous transverse tumour. On histological examination resection specimen, observe additional diffuse neuroendocrine hyperplasia dysplasia background mucosa. As grade carcinoma reported syndrome, our may indicate early stage tumourigenesis tumour syndrome.